In order to promote the creation of an ecosystem that promotes the sustainable territorial development of the Maule region, the University of Talca has developed the present project: MauleLab Regional Social Innovation Laboratory, which serves as a work-space for experimentation and the the co-creation of solutions to the present challenges. Starting with the process of collective creation, which promotes social reflection, it calls for the analysis and consideration of the realities affecting the Maule territory. Emerging from the ideation of new projects designed and executed from within the community, we will address the complex challenges observed by the laboratory.